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Advanced in vitro models To bypass the limitations of 2D cultures, advanced in vitro culture systems have been developed, including the use of 3D organized structures, known as organoids, and kidney microphysiological systems (MPS) that can recreate fluidic characteristics found in vivo (Fig

(2019) Mechanisms of ferroptosis and relations with regulated cell death: A review, Front Physiol

Consequently, it appeared to induce the release of genes that were otherwise suppressed due to the aging of the chromosomal regions